High Borosilicate Glass Microchannel Reactor with Integrated Sintered Double Heat Exchange Three Chamber Structure for Laboratory Chemical Synthesis and Process Scale Up

Product Overview

This continuous flow reaction system represents a major leap forward in laboratory-scale chemical synthesis and process intensification. Engineered with a monolithic three-chamber design, the unit integrates a central reaction layer sandwiched between two dedicated heat exchange layers. By replacing traditional stirred-tank batch systems with continuous microfluidic channels, the system dramatically increases mass transfer rates, ensures uniform temperature profiles, and reduces reaction times from hours to seconds. Its high-performance glass architecture provides visual transparency, allowing researchers to observe phase changes, precipitation, and color transitions in real time.

Designed specifically for demanding environments such as pharmaceutical R&D, fine chemical synthesis, and academic research, this equipment excels in handling highly exothermic, fast-rate, or hazardous chemical reactions. Its three-chamber sandwich configuration facilitates rapid heat dissipation, making it an invaluable tool for safely developing chemistry that would be dangerous or uncontrollable in conventional glassware. Whether performing rapid nitrations, aggressive halogenations, or complex organometallic syntheses, the system provides unmatched safety and control by minimizing in-process fluid hold-up.

Built for high-pressure durability and extreme chemical resistance, the unit utilizes advanced high-temperature molecular bonding to fuse its components into a single, seam-free glass body. Operating safely across a wide temperature spectrum and under significant pressure, the equipment maintains structural integrity without the use of vulnerable polymers, glues, or mechanical gaskets. This robust build quality ensures consistent, repeatable performance, allowing process chemists to confidently transition benchtop discoveries to pilot-scale and commercial manufacturing environments.

Key Features

• Monolithic Integrated Sintering Technology: The entire reactor body is fused through high-temperature sintering, resulting in a single piece of high-purity glass. This seamless design is completely free of glues, adhesives, or mechanical gaskets, eliminating the risk of leakage and ensuring total compatibility with highly aggressive organic solvents and acids.
• Double Heat Exchange Three-Chamber Structure: Designed with a sandwich structure (heat exchange - reaction - heat exchange), the unit utilizes two dedicated 110 mm x 140 mm heat exchange surfaces. This provides a total heat transfer area of 308 cm², delivering exceptionally fast heating and cooling responses to keep exothermic reactions within tight temperature limits.
• Optimized Microchannel Geometry: Featuring precision-engineered microchannels with a narrowest cross-section of 1.5 mm × 1.0 mm to 3.0 mm × 1.7 mm and a depth of 1.0 mm to 1.5 mm, this architecture forces reactants into constant, intense contact. The result is rapid diffusion, precise fluid dynamics, and a dramatic reduction in reaction time.
• High Pressure and Temperature Tolerance: Operating reliably between -30°C and 195°C, this system is rated for pressures up to 20.0 Bar in the reaction chamber and 3.0 Bar in the heat exchange chambers. This pressure capability supports superheated solvent reactions and rapid gas-liquid mixing without risk of structural failure.
• Outstanding Mass and Heat Transfer Coefficients: Boasting an area-to-volume ratio of 3000 to 13000 m²/m³ and a heat transfer coefficient of 1090 to 3420 W/m²·K, this reactor outperforms conventional stirred autoclaves by several orders of magnitude. This ensures ultra-fast heat removal and prevents localized hot spots that lead to byproduct formation.
• Dual Inlet/Outlet Configuration: Equipped with a dedicated 2-inlet and 2-outlet setup for both the reagents and the thermal fluid. This flexible routing allows for multi-step addition sequences, quenching steps, or multi-component mixing to be conducted in a single, continuous flow path.
• Visual Transparency for Process Optimization: Crafted from high borosilicate glass, the fully transparent flow path allows laboratory personnel to visually monitor fluid dynamics, observe crystallization or scaling, and document reaction phenomena to assist in kinetic calculations.

Applications

Technical Specifications

Physical and Operational Parameters

Comparative Performance Metrics (Continuous Flow vs. Traditional Batch)

Why Choose This Product

• Inherent Process Safety: With an internal volume of just 1 to 8 mL, this reactor minimizes the quantity of active chemicals at any given moment. This drastically reduces the potential energy release of hazardous reactions, ensuring a safer work environment.
• Exceptional Heat transfer Performance: The double heat-exchange sandwich design responds up to 30% faster to temperature adjustments than standard glass reactors. It allows for immediate cooling or heating, locking in reaction conditions and preventing side reactions.
• Precision Engineered in China: Manufactured using premium high borosilicate glass, every reactor undergoes rigorous pressure and thermal stress testing to ensure reliable, leak-proof performance under demanding conditions.
• Customizable Fluid Networks: We offer comprehensive custom engineering, including tailormade microchannel geometry, specialized flow path shapes, and adjustable hold-up volumes. We also provide integrated turnkey setups with micro-metering pumps and online sensors (pH, temperature, pressure) for full automation.
• Seamless Scale-Up Integration: The flow kinetics proven inside this reactor translate directly to pilot and production stages. By adding reactors in parallel (numbering-up), you can scale up production without redesigning the chemical process.

For more details on custom configurations, process optimization, or to request a detailed quote for your laboratory, contact KINTEK today.

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